AFB Vaccinated Queens

We are proud to partner with Dalan Animal Health to be able to supply the local region with AFB vaccinated queens.  We consider the vaccine as another tool in our kit of resources to help build and maintain strong healthy colonies.

Dalan will be hosting a webinar once per week to educate about the Transgenerational immune priming vaccine, how it works, their product development, and distribution.

Introducing Queen Bees Inoculated with Dalan Animal Health’s Oral Honeybee Vaccine 

Extract and Box LLC will now be offering local queens inoculated with the first and only registered biologic to combat AFB, developed by Dalan Animal Health. 

There are many factors that stress honeybee colonies. These may include parasites, predators, poisoning by herbicides and pesticides, loss of food due to fire and drought, and bacterial, fungal, or viral diseases. Losses caused by these stressors routinely exceed 40% or more. American Foulbrood is among the most devastating of bee bacterial infections. The bacterial spores that cause AFB have been found to be present in up to 50% of hives tested in Canada and the United States.

Developed by Dalan Animal Health, this breakthrough in honeybee care is the first and only biologic conditionally licensed by the USDA-CVB to help in the fight against AFB. The vaccine is safe, non-chemical, and suitable for use in organic agriculture.

The use of antibiotics to prevent AFB results in bacterial resistance and negatively impacts hive health overall. The only solution to treat hives with clinical AFB remains burning the hives and all related equipment.

Queen bees inoculated with Dalan’s vaccine purchased from preferred queen producers are an industry-first non-chemical prophylactic solution.

When queen bees are orally inoculated with Dalan’s vaccine, protection works through a biological mechanism called transgenerational immune priming (TGIP), whereby the queen passes immunity to her daughters before they hatch. The vaccine exposes queen bees to inactive bacteria, which enables the larvae hatched in the hive to resist infection.

Dalan is committed to providing beekeepers with innovative solutions to protect the health of their honeybees. Our product has been rigorously tested using the industry’s standard research designs to demonstrate laboratory safety and efficacy.


Vaccination of honeybees against deadly pathogens, like American Foulbrood, is an important step in protecting the health and welfare of honeybee colonies.